Unveiling the Features of Mercury-Associated Minimal Change Disease: Comparison with Primary Minimal Change Disease
نویسندگان
چکیده
منابع مشابه
Primary biliary cirrhosis associated with minimal change disease.
infection and the development of MPO-ANCA-associated GN, we compared the titres of C. pneumoniae abs in the active and remission phase of the disease in the same patients. The titres of anti-C. pneumoniae IgM and IgA, but not IgG abs in ANCA (remission) group significantly decreased compared with that in ANCA (active) [IgM ab: 1.22 0.47 vs 1.05 0.49U, P< 0.05; IgA ab: 1.70 1.20 vs 1.29 0.88 U, ...
متن کاملMinimal Change Disease.
Minimal change disease (MCD) is a major cause of idiopathic nephrotic syndrome (NS), characterized by intense proteinuria leading to edema and intravascular volume depletion. In adults, it accounts for approximately 15% of patients with idiopathic NS, reaching a much higher percentage at younger ages, up to 70%-90% in children >1 year of age. In the pediatric setting, a renal biopsy is usually ...
متن کاملRituximab in Minimal Change Disease
Treatment with rituximab, a monoclonal antibody against the B-lymphocyte surface protein CD20, leads to the depletion of B cells. Recently, rituximab was reported to effectively prevent relapses of glucocorticoid-dependent or frequently relapsing minimal change disease (MCD). MCD is thought to be T-cell mediated; how rituximab controls MCD is not understood. In this review, we summarize key cli...
متن کاملMinimal change disease: a review.
Minimal change disease (MCD) is a histopathological lesion in the kidney that is most commonly associated with nephrotic syndrome. The majority of the cases are idiopathic. Pathogenesis is not well understood, although T-cell-related mechanisms are implicated. Massive proteinuria leads to hypoalbuminemia, salt retention, disorder of hemostasis, hyperlipidemia and increased susceptibility to inf...
متن کاملA unique form of polycythemia associated with minimal change disease.
OBJECTIVE To present a case with nephrotic syndrome due to minimal change disease and polycythemia. CLINICAL PRESENTATION AND INTERVENTION A 20-year-old female was admitted to our clinic for edema and severe proteinuria present with minimal change disease since the age of 7 years. Polycythemia was found during the last activation of nephrotic syndrome. The patient was placed on glucocorticoid...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Kidney Diseases
سال: 2020
ISSN: 2296-9381,2296-9357
DOI: 10.1159/000510877